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Access myPennMedicine For Patients and Visitors. Patient Information. Conditions Treated A-Z. Peptic Ulcer Disease. Definition A peptic ulcer is an open sore or raw area in the lining of the stomach or intestine. There are two types of peptic ulcers: Gastric ulcer -- occurs in the stomach Duodenal ulcer -- occurs in the first part of the small intestine Alternative Names Ulcer - peptic; Ulcer - duodenal; Ulcer - gastric; Duodenal ulcer; Gastric ulcer; Dyspepsia - ulcers; Bleeding ulcer; Gastrointestinal bleeding - peptic ulcer; Gastrointestinal hemorrhage - peptic ulcer; G.
But if the lining breaks down, the result may be: Swollen and inflamed tissue gastritis An ulcer Stomach ulcer The stomach is the organ of the digestive system in which food travels from the esophagus and is further broken down before its nutrients are absorbed in the small intestine. Review provided by VeriMed Healthcare Network.
Editorial team. Find a Doctor Request a Callback. However, the Helicobacter pylori H. The H. Treatment for stomach ulcers includes the use of antibiotics to kill the infection, and acid-suppressing drugs. The stomach is an organ of the digestive system, located in the abdomen just below the ribs and on the left.
Swallowed food is squeezed down the oesophagus and pushed through a sphincter small muscle ring into the stomach, where it is mixed with powerful gastric juices containing enzymes and hydrochloric acid. The stomach is a muscular bag, so it can churn the food and break it down mechanically as well as chemically. Once the food is the consistency of smooth paste, it is squeezed through a second sphincter into the first part of the small intestine duodenum.
The lining of the stomach — the mucosa or gastric epithelium — is layered with multiple folds. Ulcers occur in this lining. The Helicobacter pylori bacterium H. The discovery of this micro-organism in revolutionised many aspects of gastroenterology, including the treatment of stomach ulcers.
It is thought that about one in three people over the age of 40 years is infected with this strain of bacteria in Australia. The germs live in the lining of the stomach and the chemicals they produce cause irritation and inflammation. Other disorders caused by this infection include inflammation of the stomach gastritis and dyspepsia indigestion.
Researchers believe the germ could also play a contributing role in the development of stomach cancers. The infection is more common among poor or institutionalised people. The mode of transmission is so far unknown, but is thought to include sharing food or utensils, coming into contact with infected vomit, and sharing of water such as well water in undeveloped populations.
This is a serious complication of ulcer disease and is particularly deadly in the elderly or those with multiple medical problems. Bleeding from stomach ulcers is more common in people treated with blood thinning agents, such as warfarin, aspirin or clopidogrel Plavix and those people should also consider using regular anti-ulcer medication to prevent this complication.
A severe, untreated ulcer can sometimes burn through the wall of the stomach, allowing digestive juices and food to leak into the abdominal cavity. This medical emergency is known as a perforated ulcer. Treatment generally requires immediate surgery. Special diets are now known to have very little impact on the prevention or treatment of stomach ulcers. Treatment options can include:.
This page has been produced in consultation with and approved by:. The type of pain felt in the abdomen can vary greatly. Overview Ulcers Open pop-up dialog box Close.
Ulcers A peptic ulcer is a sore on the lining of your stomach, small intestine or esophagus. Email address. First Name let us know your preferred name.
Last Name. Thank you for subscribing Your in-depth digestive health guide will be in your inbox shortly. Sorry something went wrong with your subscription Please, try again in a couple of minutes Retry. Request an Appointment at Mayo Clinic. Share on: Facebook Twitter. Show references Kellerman RD, et al. Gastritis and peptic ulcer disease. In: Conn's Current Therapy Elsevier; Accessed July 8, Peptic ulcer disease. American College of Gastroenterology. Peptic ulcers stomach ulcers. Feldman M, et al.
Saunders Elsevier; Nehra AK, et al. Proton pump inhibitors: Review of emerging concerns. Mayo Clinic Proceedings. Peptic ulcer disease adult. Mayo Clinic; Peptic ulcers. Natural Medicines. Accessed July 21, Brown AY. AllScripts EPSi. Rochester, Minn.
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