Measure content performance. Develop and improve products. List of Partners vendors. Glucosamine is a dietary supplement that is often combined with another supplement, chondroitin , to treat osteoarthritis.
Glucosamine is made from the shells of shellfish and chondroitin is derived from cow trachea. Evidence published in the New England Journal of Medicine in suggested that glucosamine alone or combined with chondroitin can help relieve osteoarthritis pain in a subgroup of people with moderate to severe knee osteoarthritis.
It should be noted that based on further research, the American Academy of Orthopedic Surgeons currently advises against the use of glucosamine sulfate, chondroitin sulfate, and glucosamine hydrochloride in treating symptomatic knee osteoarthritis. Supplements advertised for improved joint health can be confusing and even downright misleading. And that can be a problem.
If you take too much, you may be increasing the risk of side effects. Results of a study from Tufts-New England Medical Center conclude that typical doses listed on over-the-counter supplements are probably not strong enough to help relieve arthritic joint pain and stiffness. To this end, the recommended dosages are based more on what amount of drug causes little to no harm yet is believed to offer therapeutic benefits.
The initial dose is typically 1, milligrams mg of glucosamine and 1, mg of chondroitin daily for one to two months. If a response is obtained, the dose can be reduced to 1, mg of glucosamine and mg of chondroitin per day. According to the Tufts study, it is still unclear as to whether higher doses are more effective and whether that level of dosing may cause potential harm. Because supplements are not regulated by the Food and Drug Administration, the amount of active ingredient cannot always be verified.
Most studies have shown that glucosamine needs to be taken for two to four months before its full benefits are realized, although some will experience improvement sooner. Potential side effects of glucosamine-chondroitin include:.
These risks may increase at higher doses. Glucosamine should be avoided if you are allergic to shellfish. People on the blood thinner Coumadin warfarin may have an increased risk of bleeding. Stop treatment and call your healthcare provider if you experience sudden swelling in the legs or irregular heartbeats. Call or seek emergency care if you develop hives, shortness of breath, rapid heartbeats, or the swelling of the face, tongue, or throat.
Always consult your own healthcare provider. Your healthcare provider knows your medical history and your current medication regimen. Make your healthcare provider aware that you wish to add a supplement to your treatment regimen, then follow their advice.
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Glucosamine and Chondroitin for Osteoarthritis Pain Research is mixed on whether these supplements help with OA pain and stiffness, but they are safe to try. What Are Glucosamine and Chondroitin? How Do They Work? Which Form Is Best?
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